产品货号：
Z24178
中文名称：
PIAS1抗体
英文名称：
Anti-PIAS1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PIAS1 Antibody |
| 指标别名 | DDXBP1;DEAD/H box binding protein 1;E3 SUMO protein ligase PIAS1;Gu binding protein;GU/RH II;PIAS1;ZMIZ3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | PIAS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PIAS1(636-651aa DTASIFGIIPDIISLD),identical to the related mouse and rat sequences. |
| 实际分子量 | 72KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.It is mapped to 15q23.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1(signal transducer and activator of transcription-1)] family.This member contains a putative zinc-binding motif and a highly acidic region.PIAS1 inhibited STAT1-mediated gene activation in response to interferon when expressed in mammalian cells.It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.On the other hand,PIAS1 also can function as a SUMO ligase,or possibly as a tightly bound regulator of it,toward p53. |
| Uniprot ID | O75925 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein inhibitor of activated STAT,1 |
| 蛋白名全称 | E3 SUMO-protein ligase PIAS1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：PIAS1抗体，PIAS1多抗，Anti-PIAS1 Antibody